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When you combine appetite suppression from GLP-1 activation with the insulin-sensitizing effects of GIP stimulation and the thermogenic boost from glucagon receptor engagement, you get a compounding metabolic effect that no single-receptor or dual-receptor agonist can match
Clinical trials of brand-name semaglutide demonstrated average weight loss of 15 to 17 percent of body weight over 68 weeks in the STEP trials
Siddiqui MS, Van Natta ML, Connelly MA, et al
Not all compounding pharmacies are made the same, says Janice Jin Hwang, a clinician and endocrinologist at the University of North Carolina at Chapel Hill
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