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Vitamin B 12 deficiency can develop for the following reasons: Absence of intrinsic factor, also called pernicious anemia: Intrinsic factor is a protein secreted by cells of the stomach lining
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It is more common in people over 50, and ageing may contribute to nerve sensitivity or damage
Studies confirmed that animals lacking these receptors showed no lipolytic response, validating this as the primary pathway
Peripheral neuropathy affects millions of people and is a growing concern, particularly amongst individuals living with diabetes and those who have long term nutritional absorption issues
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