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doi:10.1152/ajpendo.1997.273.5.E981 22

Thus, in situ produced microbial folate may favourably influence the cellular nutrition of the local colonocytes and may be important in maintaining intestinal homeostasis and modulating gut microbiome function, e.g., through regulation of colon mucosal proliferation (i.e., colorectal cancer prevention) and its anti-inflammatory effects 248,249,256,257,277,278,279,280,281,282,283,284,285,286

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However, full recovery can take several months, particularly if the deficiency has caused nerve-related symptoms