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Guidance from medical centers and clinical research organizations highlights the importance of individualized assessment and ongoing communication between patients and healthcare professionals

The ADA standard for the treatment of diabetes updated in 2020 indicated that patients with T2DM diagnosed with CVD or those with CVD risk factors can use GLP-1RAs and SGLT2 inhibitors with evidence of cardiovascular benefits to reduce cardiovascular risk, regardless of HbA1c levels or individualized HbA1c control objectives [189]

Pretreatment with lactoferrin-CAY10603-loaded PLGA nanoparticles significantly reduced ROS levels by ~3.0-fold, indicating strong antioxidant activity

A meta-analysis by Ghavami et al

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