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Dihexa was administered to the APP/PS1 mice intraperitoneally from 6 to 9 months of age and 0.9% saline was administered to the wild type group once per day over a three month time period
The dance requires the biosimilar applicant to share its full application and manufacturing information with the reference product sponsor (RPS) within 20 days of FDA acceptance of the BLA
Both are FDA-approved for chronic use, but they work differently
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Simultaneously, these agents suppress glucagon secretion , a hormone that raises blood glucose, thereby preventing excessive glucose production by the liver
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