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The TIMP was added solely based on the concerns raised by the IRB, and this motor test will mainly be used as a tool for the DSMB when deciding whether the study should continue or not

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Vitamin B12 shot side effects Most people tolerate vitamin B12 injections well, but possible side effects include: Mild: soreness or redness at injection site, mild diarrhea, nausea, headache, itching Rare but serious: allergic reactions (rash, swelling, difficulty breathing), low potassium (hypokalemia), dizziness or heart rate changes Get emergency medical help if you have signs of an allergic reaction to Vitamin B12: hives

For many others, high-dose oral B12 works just as well (NIH ODS