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Importantly, these effects occurred at rates similar to placebo groups, suggesting that many cases represented background occurrence rather than treatment-specific effects
Nausea (most common, especially during first 1 to 2 weeks of a new dose) Diarrhea or, just as often, constipation Vomiting (less common but more likely at 9 to 12 mg) Reduced appetite, food noise quieting down (this is the goal, not a side effect) Skin sensitivity (dysesthesia): tingling, prickly feeling, or sunburn-like skin
This reaction is temperature-dependent and essentially irreversible once it occurs
Participants who took vitamin B6 saw a statistically significant reduction in anxiety symptoms, indicating improved functioning of GABA, the neurotransmitter associated with calming and relaxing