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La gran mayora de los efectos adversos son gastrointestinales, de intensidad leve a moderada, y con tendencia natural a la atenuacin en las primeras semanas de cada nueva dosis

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Acta 1, 110

Instead of adding amino acids, DES removes the first three from the N-terminus, creating a truncated 67 amino acid peptide

Use: To reduce the risk of sustained estimated eGFR decline, ESRD, and CV death in patients with type 2 diabetes mellitus and chronic kidney disease Usual Adult Dose for Metabolic Dysfunction-Associated Steatohepatitis Wegovy injection: Initial dose (weeks 1 through 4): 0.25 mg subcutaneously once a week Dose escalation: Weeks 5 through 8: 0.5 mg subcutaneously once a week Weeks 9 through 12: 1 mg subcutaneously once a week Weeks 13 through 16: 1.7 mg subcutaneously once a week If 2.4 mg is not tolerated: 1.7 mg subcutaneously once a week