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The supramammillary nucleus, located in the hypothalamus, is a new candidate that appears to be responsible for GLP-1 mediated anxiety effects because selective activation of GLP-1Rs in this nucleus by exendin-4 resulted in intensified anxiety-like behavior both in male and female rats
Can InBody replace DEXA scans for GLP-1 monitoring
Originally developed for type 2 diabetes management, Semaglutide gained widespread attention after the STEP 1 clinical trial (NEJM, 2021) demonstrated an average weight loss of 14.9% of body weight over 68 weeks at the 2.4mg weekly dose
Semaglutide, at least, only works in the one direction
Discuss with your provider whether the modest cost difference justifies the convenience of tablets versus the efficacy advantage of injections
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