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Depletion of tryptophan (a Candida metabolic substrate) reduces serotonin synthesis, while chronic gut inflammation elevates inflammatory cytokines (IL-6, TNF-) that independently suppress mood via neuroinflammatory pathways

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Some contrary conclusions derive from using genetic markers as a proxy for circulating concentrations of UA

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EGb 761 in control of acute mountain sickness and vascular reactivity to cold exposure