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doi: 10.1155/2021/8874339 5 AderF.Bouscambert-DuchampM.HitesM.Peiffer-SmadjaN.PoissyJ.BelhadiD.et al
Abbreviations AAb+: Autoantibody positive AFM: Afamin ApoB: Apolipoprotein B-100 ApoC1: Apolipoprotein C1 ApoL1: Apolipoprotein L1 BMI-SDS: BMI expressed as standard deviation score CETP: Cholesteryl ester transfer protein F2: Prothrombin FDR: False discovery rate GPx: Glutathione peroxidase GPX3: Glutathione peroxidase 3 GSH: Glutathione HGFAC: Hepatocyte growth factor activator HRG: Histidine-rich glycoprotein IGFBP1: IGF-binding protein 1 IGFBP2: IGF-binding protein 2 IGFBP3: IGF-binding protein 3 INNODIA: Innovative approaches to understanding and arresting type 1 diabetes LMM: Linear mixed effects model MASP2: MBL associated serine protease 2 MMTT: Mixed meal tolerance test ND: Newly diagnosed with type 1 diabetes PPAR: Peroxisome proliferator-activated receptor QC: Quality control Se: Selenium SERPING1: Plasma protease C1 inhibitor SRM: Selected reaction monitoring TGFBI: TGF--induced protein ig-h3 TTR: Transthyretin UFM: Unaffected family member References Rodriguez-Calvo T, Richardson SJ, Pugliese A (2018) Pancreas pathology during the natural history of type 1 diabetes
No major mechanistic incompatibility between NAD+ and glutathione is currently apparent
Some patients report a warm or flushing sensation immediately following injection, which is normal
Absorption happens through the oral mucosa and bypasses first-pass liver metabolism
