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The severity of traumatic lesions, such as subarachnoid and intraventricular hemorrhage, brain laceration, and hemorrhagic laceration, appeared to be less pronounced in the BPC-157 group

Well-powered, controlled trials are needed to confirm efficacy and safety, identify optimal subgroups, and evaluate long-term outcomes

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1 Although MMNSTs are histologically and clinically distinct from malignant peripheral nerve sheath tumors (MPNSTs), treatment strategies are often extrapolated from the MPNST literature owing to the rarity of MMNSTs

TSC is currently in a phase III clinical trial (NCT03393000)