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PI3K/Akt/mTOR + MAPK/ERK Activates both the metabolic (PI3K/Akt/mTOR - protein synthesis, glucose uptake) and proliferative (MAPK/ERK) IGF-1 signalling cascades
Cancer 76 RaemdonckK.VandenbrouckeR
Swapping an acidic residue for a basic one at that position disrupts the interaction
Researchers have no way to visually assess whether a temperature excursion has compromised their sample
ROS is a product of cellular redox metabolism, and moderate amounts of ROS in the epididymis can play a role in sperm maturation and capacitation by regulating cAMP levels (Taylor et al., 2013)
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