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Trial design: 751 adults with obesity (BMI 30, or 27 with at least one comorbidity) No type 2 diabetes 72-week follow-up Tirzepatide 10mg or 15mg vs Semaglutide 2.4mg Results at 72 weeks: When looking at tirzepatide weight loss results from SURMOUNT-5 alongside semaglutide weight loss results from the STEP trials, the gap is consistent and statistically significant across every subgroup sex, age, baseline BMI, and presence of metabolic comorbidities

Some researchers follow even more conservative titration using microdosing approaches

User 8, a 22-year-old with Grade 1 tears across multiple sites, used a pre-blended BPC-157 and TB-500 product at 600mcg total once nightly

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Pediatric Dosage: Infants and children excrete carnitine very rapidly, so they require high doses, typically ranging from 100 to 400 mg/kg/day , divided into three or four doses throughout the day [4] [2]