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Description

The above biological processes can lead to excessive iron accumulation in the cells, which provides a basis for the occurrence of ferroptosis 52

Simultaneously, 3 Glucose and 6 Phosphate molecules react

The standard conversion from rat to human doses uses a factor of approximately 6.2, meaning a rat dose of 10 g/kg translates to roughly 1.6 g/kg in humans

Biologic therapies effectively target specific inflammatory mediators, but do not directly address metabolic dysfunction or oxidative stress, both of which contribute to HS severity