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Environ Geochem Health
Cycles exceeding 16 weeks without a washout carry a documented risk of receptor downregulation
Evidence from clinical trials in adult patients suggests that supplementation with n-3 PUFAs during chemotherapy may improve treatment tolerability, regardless of the type of cytostatic drug used [9,10,11,12,13,14,15,16]
These complexes facilitate the activation of caspase-3/7, cleavage of GSDMD and GSDME, and phosphorylation of MLKL, leading to membrane pore formation and the progression of PANoptosis [39]
However, apparent injury of normal organs could be observed in mice that were treated with free DOX (Supplementary Fig
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