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Our findings make sense from a theoretical standpoint, since GLP-1 medications do have an anti-inflammatory mechanism, but we cant guarantee the association with uveitis. More research with different methodologies, such as retrospective chart reviews and prospective trials, is needed to confirm the findings and inform clinical practice
Additionally, NK cells produce IFN-, which activates p53 signaling in tumor cells, upregulating pro-apoptotic proteins and downregulating anti-apoptotic ones, thereby enhancing apoptosis [38, 273, 274]
While BMI-mediated effects might be anticipated, our mediated analysis found that BMI and current tobacco smoking mediated 20.28% and 6.65%, respectively, of the total effect of GLP-1RAs on SA risk
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Curcumin triggers the activation of PPAR-, which subsequently reduces the production of matrix metalloproteinases
