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Some describe mild gastrointestinal discomfort, including nausea, bloating, and gas, particularly when starting the supplement or taking it on an empty stomach

But the composition of that change matters enormously

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Parameters reported in animal studies are specific to those study designs and are not validated for human use

The cytotoxicity of Ru(II)-OH, NP2, and NP4 against 143B and K7M2 cells in a 21% O 2 or 1% O 2 atmosphere was studied using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay