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This is one reason head-to-head binding assays dont always match head-to-head secretion experiments and why researchers occasionally get surprised when GHRP-6 outperforms GHRP-2 in certain model contexts despite lower receptor binding affinity on paper
doi: 10.3390/ijms21228637 17
Grisoni F, Neuhaus CS, Hishinuma M, Gabernet G, Hiss JA, Kotera M, Schneider G (2019) De novo design of anticancer peptides by ensemble artificial neural networks
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