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Description

Converting mg/mL to mcg/mL: Multiply by 1,000 (e.g., 1 mg/mL = 1,000 mcg/mL)

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Modulating a complex system carries the possibility of unintended effects that require careful study

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A retrospective study looking at concomitant use of proton pump inhibitors (PPIs) alongside metformin in 614 people with type 2 diabetes in the US found a significant reduction in B12 levels of 34% in patients taking both medications, compared to controls taking either drug alone (Long et al, 2012)

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Post-reconstitution: 2-4 weeks at 2-8C, 1-3 months at -20C (aliquoted)

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