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(Many people use Ozempic off label for weight loss, though it is not FDA-approved for such.) These medications seem to promote weight loss through two mechanisms that, again, mimic the action of endogenous GLP-1: They delay gastric emptying: The sensation of fullness caused by slower gastric emptying can prompt people to eat less, thus helping them lose weight over time
Lying down too soon after eating a meal can make the food reflux back through the oesophagus, causing heartburn and making you feel nauseous
11 Alternatively, one could consider swapping rapid acting insulin for regular insulin due to the difference in pharmacokinetics that may be a benefit in the setting of delayed gastric emptying [see figure below]
For example, AOD-9604 directly stimulates fat breakdown , 5-Amino-1MQ ramps up cellular fat burning , CJC-1295 boosts fat-burning growth hormone , and MOTS-c improves exercise capacity and insulin action
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