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Baicalin is not easily absorbed orally and can be absorbed into the blood only after enzymatic hydrolysis into baicalein in the intestine, which is rapidly transformed into baicalin in the body
It is driven by lipid peroxidation and oxidative stress, which can directly kill tumor cells and modulate the tumor microenvironment to suppress progression [21, 22]
2011 James J DiNicolantonio, James H O'Keefe, William Wilson
Histopathological findings further validated this synergy, with PTX-CSNPs preserving glomerular and tubular architecture, while free PTX showed residual tubular apoptosis
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