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To achieve a plasma level of 0.7mM (less than the 1mM used int he paper), you have to give a rat 150mg/kg/day IV, which is the equivalent of a 1451mg IV SAMe daily dose to a 60kg human, but since the oral absorption is around 5%, that's the equivalent of more than a 29,000mg daily oral dose

Label the vial and store refrigerated at 28C, protected from light

Growth hormone & IGF research: official journal of the Growth Hormone Research Society and the International IGF Research Society , 19 (5), 426431

Most recommendations emphasize conservative dosage , timed cycles, and professional oversight