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In a November 2024 article featured in The New England Journal of Medicine, researchers found that tirzepatide reduced the risk of cardiovascular death or worsening heart failure in patients with heart failure with preserved ejection fraction and obesity

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Insiders warn: Never fall into the trap of liquid fasting. If you drink black coffee mixed with allulose on an empty stomach first thing in the morning, not only will you completely shut down your GLP1 response, but you might even turn into a shooter (triggering severe diarrhea)

This concern appears to stem from glutathione's skin-brightening mechanism, which works by inhibiting melanin production through tyrosinase modulation a temporary, dose-dependent, and generally reversible effect, not an autoimmune depigmentation process like vitiligo