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Meanwhile, esculetin decreases GSH contents by suppressing the Nrf2 signal pathway and inhibiting the expression of its target antioxidant proteins (GPX4 and HO-1)

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Protein hydrolysates from animal processing by-products as a source of bioactive molecules with interest in animal feeding: a review

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SAC, a major organosulfur compound in aged garlic extract, prevented renal damage caused by ROS in cisplatin-treated rats, by limiting cisplatin-induced reduction of glutathione level, Nrf2 expression, and activity of several antioxidant enzymes (catalase, glutathione reductase, glutathione peroxidase) (25)