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When overactive, it lowers NAD+ levels and promotes fat accumulation , particularly in visceral (deep belly) fat

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The secondary endpoints include achievement of 20% weight reduction, relative change in body weight, change in waist circumference, change in HbA1c, change in systolic blood pressure, change in the quality of life (IWQOL-Lite-CT), and change in short-form physical functioning score (SF-36v2)

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The reconstitution math and per-IU equivalences in this article describe physical concentrations in a vial, not human therapeutic doses