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Internalization of Y2-R A human Y2-R (G s -coupled) doseresponse (5.51 pM551 nM) cell-based agonist-activated internalization assay was performed in duplicate with PYY 3-36 as a positive control
Findings were assessed across multiple independent datasets, including FinnGen, Psychiatric Genomics Consortium (PGC), and UK Biobank, and were synthesized through meta-analysis
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Psarra, A., Nikolaou, A., Kokotou, M
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