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AVAILABILITY OF DATA All data not contained either in this manuscript or elsewhere in the published literature (e.g., microsphere quantification, raw pressure-volume loop tracings, raw proteomic values, etc.) but that are germane to the full evaluation of results are fully available upon request made to the corresponding author

Mov Disord 39(11):19601970

Others feel the effects gradually over the next few days

Ongoing maintenance cycles (2 to 3 times per year) help sustain the improvements and counter the natural age-related decline in collagen production

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