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Berberine ameliorates high glucose-induced cardiomyocyte injury via AMPK signaling activation to stimulate mitochondrial biogenesis and restore autophagic flux

MOTS-c optimizes mitochondrial function and metabolic efficiency through AMPK activation, improved insulin sensitivity, and support for mitochondrial biogenesis

[8] [10] [11] [12] This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA

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