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Several trials with tirzepatide are also ongoing, including SURPASS-6, SURPASS-J, SURPASS-AP, and SURPASS-CVOT, all of which will look at the effects of this agent compared to other agents (insulin lispro, dulaglutide, insulin glargine) on weight, HbA1c, and the occurrence of major adverse cardiovascular events (MACE), respectively [38]
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