Jorgensen N, Joensen UN, Jensen TK, et al
Once approved, you can pay $50 per month for Foundayo, Wegovy (injection and tablet formulations), and Zepbound (KwikPen)*^
This selectivity has made it a point of interest in discussions around controlled growth hormone modulation
Developed by Eli Lilly, it is a 39-amino-acid synthetic peptide with a C20 fatty diacid side chain attached via a linker at lysine-20, enabling binding to albumin for once-weekly dosing pharmacokinetics (Jastreboff AM et al., NEJM 2022
GLP-1 RA Addition to Background Sulfonylurea Therapy Similar to the discussion above about background insulin, it is prudent in many cases to hold or reduce the dose of background sulfonylurea therapy (an initial 50% dose reduction is reasonable in many patients) when starting a GLP-1 RA