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Although data on HR were not provided in most studies of twice-daily exenatide, HR elevation was generally more apparent in the GLP-1 RA treatment arms, compared with the comparator arms (Table 2)
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The response rate was equally impressive: 91.7% of participants on the 12 mg dose achieved at least 10% total body weight reduction
The quantification and normalization (DESeq method) and further downstream analyses of identification of differentially expressed genes (DEGs) were done by using R package
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