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Metformin, commonly used in diabetes management, has been associated with reduced vitamin B12 absorption, potentially through effects on calcium-dependent vitamin B12-intrinsic factor absorption in the terminal ileum

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Frontiers in Cardiovascular Medicine, 6

Preclinical studies have examined the peptide in models of gastrointestinal injury, epithelial disruption, and anastomosis healing where researchers analyze mucosal architecture, vascular integrity, and epithelial continuity following tissue damage [1]

Low levels of B12 could be behind feelings of anxiety or depression