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An estimated 13% of patients stopped using their GLP-1 medication due to side effects of the drug [22]

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if more than 3 days, skip that dose Daily GLP-1s: If you miss a dose, follow your PIL instructions If you take insulin or sulfonylureas alongside GLP-1 medications, do not adjust these doses yourself without medical advice, as this could increase hypoglycaemia risk Report persistent side effects to your GP rather than stopping treatment abruptly Some patients may require dose adjustment if they develop acute illness, undergo surgery, or experience significant changes in kidney function

In the study, major adverse cardiovascular events (MACE) occurred less frequently than anticipated in both retatrutide and placebo arms

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