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Mazdutide (LY3502970): A dual agonist targeting GLP-1R and GCGR
Increased Skin Pigmentation Melanotan 2 is most commonly used for its ability to provide users with a deep tan without extended sun exposure
Tirzepatide, which mimics GLP-1 plus the gut hormone GIP, was approved to treat type 2 diabetes (under the name Mounjaro) in May 2022
The specific rationale for adding glucagon receptor agonism to the GIP/GLP-1 dual agonist framework was grounded in preclinical evidence that glucagon promotes energy expenditure and hepatic lipid oxidation
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