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A global meta-analysis published in BMC Medicine examined data from 11 randomized controlled trials across six anti-obesity medications, including semaglutide, orlistat, and tirzepatide

The likelihood of developing this adverse effect increases with higher doses, regardless of whether the cardiotoxicity manifests acutely or chronically, particularly in cancer survivors

Por otro lado, el efecto antihiperglucemiante de los inhibidores del cotransportador sodio-glucosa tipo 2 (iSGLT2) disminuye a medida que lo hace el filtrado glomerular (FG), con FGe 15ml/min/1,73m2)78

So Paulo, SP, Brasil III Departamento de Sade Pblica, Faculdade de Medicina, Universidade Estadual Paulista