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Briefly, quantification of signal bias was performed using pharmacologically derived parameters of agonist affinity (Ka) and efficacy (tau) for each ligand in each of the three signalling pathways (cAMP accumulation, ERK1/2 phosphorylation, Intracellular Ca 2+ mobilisation)
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A: It may help some people stay consistent with movement if discomfort or recovery were limiting, but it doesn't provide predictable weight loss by itself
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