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Stick to your dosing protocols based on the chosen administration route
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A considerable proportion is excreted in unchanged form and another in the form of conjugated metabolites
This brings us to one of the lesser-known long-term effects of B12 supplements: potential stress on the kidneys, especially if taken in mega doses every day without checking blood levels first
We are not aware of any movement to make these tests more available even though the NICE Guideline on B12 Deficiency recommended the use of these tests, together with presentation of symptoms, to diagnose B12 deficiency and Pernicious Anaemia
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