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Both enzymes catalyze ATP-dependent carboxylation of acetyl-CoA to form malonyl-CoA

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To experimentally confirm this, cell proliferation assays were conducted using U87 and LN229 glioblastoma cell lines

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10.1002/fsn3.1006 29 LiuJ.HuY.ZhangH.XuY.WangG

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Atherosclerosis 140 , 135145 (1998)

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