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This outcome is more common with severe structural issues, very long-standing chronic pain, or conditions better addressed by other interventions

If youre currently taking insulin or sulfonylureas, your provider will need to adjust those doses when starting tirzepatide to prevent hypoglycemia, as tirzepatide significantly improves insulin sensitivity and reduces fasting blood glucose

Allergy-wise, the risk is very low

They significantly slow down stomach emptying, leading to a prolonged sense of fullness after meals, reducing food intake, and preventing overeating