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Steric hindrance is the major limiting factor in the synthesis of the B 12 coenzyme analogs
In addition, upregulation of ABCB1 is associated with the transcriptional fusion of ABCB1 and SLC25A40, which was identified through whole-genome analysis in patients with high-grade serous ovarian cancer (HGSOC) who underwent prior chemotherapy and targeted therapy [28]
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It helps remove toxins and free radicals from the skin
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