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In fact, one study found that peoples bodies absorbed about 49% of a 1-mcg dose of cyanocobalamin, compared to 44% of the same dose of methylcobalamin ( Conversely, another study comparing the two forms reported that about three times as much cyanocobalamin was excreted through urine, indicating that methylcobalamin may be retained better within your body ( However, some research suggests that differences in bioavailability between the two forms may be insignificant and that absorption could be influenced by factors such as age and genetics ( Unfortunately, recent research directly comparing these two forms of vitamin B12 is limited

However, as with oral glutathione, we do not have the required amount or quality of research to deem IV glutathione safe for skin lighting in the pregnant, nursing, or even non-pregnant or non-nursing population

Daily application of a broad-spectrum sunscreen is essential to reduce the risk of further pigmentation

Jardine M, Zhou Z, Lambers Heerspink HJ, Hockham C, Li Q, Agarwal R, et al

3bd and Extended Data Fig