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For this reason, they are recognized as a model system for investigating the effect of disease triggers such as hyperglycemia, oxidative stress, and hypoxia on the endothelium, as well as angiogenesis, and cellular immune responses mediated by leukocytes [83,84,85,86,87]

Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 24 mg for weight management: a randomised, controlled, phase 1b trial