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Headaches during initial use Headaches represent the second most commonly reported side effect
Sounds bad
Gastroenterology 129 , 550564 (2005)
Temporary in first weeks from calorie deficit
Kidney Dysfunction: While the kidneys do not directly excrete vitamin B12 efficiently, impaired renal function may lead to elevated serum B12 levels by reducing the clearance of B12-binding proteins or altering their metabolism, thereby contributing to B12 accumulation 8
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