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Without human trials, every approach is an estimate

BSO also improved glucose tolerance by 37% in AK mice in the long-term cohort, without affecting insulin tolerance

Aspelund, A., et al

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4d), among which six ferroptosis-inhibiting genes (Slc7a11, Slc40a1, Gclm, Fth1, Gclc, and Gss) were upregulated, one ferroptosis-promoting gene (Slc39a14) was downregulated, and one ferroptosis-promoting gene (Hmox1) was upregulated