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This interval allows: GI side effects (nausea, vomiting, diarrhea) from the current dose level to subside The body to adapt to the rate of gastric emptying at that dose Clinicians to assess tolerability before increasing further Time to reach maximum dose week 20 (after five four-week steps: 1mg, 2mg, 4mg, 8mg, 12mg)

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This can reduce the amount of food a person eats throughout the day