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These effects were achieved through the regulation of the Akt/mTOR/GSK-3 signaling pathway, positioning ESP as a promising therapeutic agent for addressing cognitive decline associated with AD (Luo et al., 2022)

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Insulin-like Growth Factor 1 Long R3 (IGF-1 LR3) is a synthetic peptide hormone designed to mimic and enhance the effects of naturally occurring IGF-1, a critical growth factor involved in muscle development, recovery, and cellular repair