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The standard body surface area scaling method, endorsed by the FDA for first-in-human dose estimates, typically divides the rodent dose by a factor of approximately 6.2 when converting from rat to human
Aftercare Advice No anti-inflammatory drugs for at least 72 hours post treatment
Lifestyle factors
Diarrhea , affecting about 18-24% of patients, presents a different but equally relevant risk
Magoulas and El-Hattab 2012
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