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As we age, the natural production of human growth hormones (HGH) in the pituitary glands can decline anywhere from 12 to 15 percent every 10 years, which can lead to impairments in metabolic functions throughout the body

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Key phenotypes (hippocampus-dependent deficits, CA1 degeneration, GSH depletion) and EEG abnormalities (elevated / waves) directly mirror human SAE (Synek, 1988

Researchers compare treated samples against controls to assess changes in cartilage matrix composition at the molecular level