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Oral Bioavailability and Protease Resistance Unlike true peptides, Dihexa resists gastrointestinal peptidase degradation due to its peptidomimetic structure
The reduction was consistent for both pulmonary embolisms and deep venous thrombosis, and the benefits were observed both in obese patients and those who were not
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(2025) doi: 10.1001/jamapsychiatry.2024.4789 Summary Keywords alcohol use, All of Us cohort, cocaine dependence, drug repurposing, GLP-1 receptor agonists, nicotine dependence, opioid use, substance use disorders Citation Abegaz TM, Ahmed M, Bhagavathula AS and Frietze G (2026) Association between GLP-1 receptor agonist use and substance use disorders among individuals with type 2 diabetes or obesity: a nested case-control study in the All of Us research program
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